Dimorphic conlang?

Have any of the conlangers here ever developed a language wherein a sentient
species' physiological or social dimorphism was reflected in the language in
other than a minor way (e.g. m/f manifesting as specifically male pronouns &
female pronouns?

Thanks.

____________________________________
One should respect public opinion in so
far as is necessary to avoid starvation
and to keep out of prison, but anything
beyond this is voluntary submission to
an unnecessary tyranny.
-- Bertrand Russell

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